Anaphylatoxin-induced histamine release with human leukocytes: studies of C3a leukocyte binding and histamine release.

Purified human C3a and synthetic COOH-terminal peptides of C3a, i.e., a pentapeptide, Leu-Gly-Leu-Ala-Arg (5R), and an octapeptide, Ala-Ala-Ala-Leu-Gly-Leu-Ala-Arg (8R) induced histamine release from human basophil granulocytes. On a molar basis, 5R was one-tenth and 8R was one-fifth as active as C3...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Glovsky, M M, Hugli, T E, Ishizaka, T, Lichtenstein, L M, Erickson, B W
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1979
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372185/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/89118/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109527
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