Anaphylatoxin-induced histamine release with human leukocytes: studies of C3a leukocyte binding and histamine release.

Purified human C3a and synthetic COOH-terminal peptides of C3a, i.e., a pentapeptide, Leu-Gly-Leu-Ala-Arg (5R), and an octapeptide, Ala-Ala-Ala-Leu-Gly-Leu-Ala-Arg (8R) induced histamine release from human basophil granulocytes. On a molar basis, 5R was one-tenth and 8R was one-fifth as active as C3...

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Bibliografske podrobnosti

izdano v:	J Clin Invest
Principais autores:	Glovsky, M M, Hugli, T E, Ishizaka, T, Lichtenstein, L M, Erickson, B W
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Clinical Investigation 1979
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372185/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/89118/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109527
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