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Effect of age on glucose-stimulated insulin release by the beta-cell of the rat.

To assess the effect of age on beta-cell insulin release, collagenase-isolated islets of Langerhans were obtained from rats aged 2--18 mo and incubated with increasing concentrations of glucose. Similar islets were analyzed for insulin content or subjected to morphometric measurements to identify bo...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Reaven, E P, Gold, G, Reaven, G M
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1979
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372155/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/379046/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109498
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