A role for transglutaminase in glucose-stimulated insulin release from the pancreatic beta-cell.

Preincubation of rat islets of Langerhans with the potent inhibitors of islet transglutaminase activity, monodansylcadaverine (30-100 microM) and N-(5-aminopentyl)-2-naphthalenesulphonamide (100-200 microM), led to significant inhibition of glucose-stimulated insulin release from islets. In contrast...

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Detalles Bibliográficos
Main Authors: Bungay, P J, Owen, R A, Coutts, I C, Griffin, M
Formato: Artigo
Idioma:Inglês
Publicado: 1986
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1146677/
https://ncbi.nlm.nih.gov/pubmed/2874792
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