Ultra-sensitive detection of rare T cell clones

Advances in high-throughput sequencing have enabled technologies that probe the adaptive immune system with unprecedented depth. We have developed a multiplex PCR method to sequence tens of millions of T cell receptors (TCRs) from a single sample in a few days. A method is presented to test the prec...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Robins, Harlan, Desmarais, Cindy, Matthis, Jessica, Livingston, Robert, Andriesen, Jessica, Reijonen, Helena, Carlson, Christopher, Nepom, Gerold, Yee, Cassian, Cerosaletti, Karen
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721519/
https://ncbi.nlm.nih.gov/pubmed/21945395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2011.09.001
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires