Functional genomics identifies five distinct molecular subtypes with clinical relevance and pathways for growth control in epithelial ovarian cancer

Epithelial ovarian cancer (EOC) is hallmarked by a high degree of heterogeneity. To address this heterogeneity, a classification scheme was developed based on gene expression patterns of 1538 tumours. Five, biologically distinct subgroups — Epi-A, Epi-B, Mes, Stem-A and Stem-B — exhibited significan...

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Main Authors: Tan, Tuan Zea, Miow, Qing Hao, Huang, Ruby Yun-Ju, Wong, Meng Kang, Ye, Jieru, Lau, Jieying Amelia, Wu, Meng Chu, Bin Abdul Hadi, Luqman Hakim, Soong, Richie, Choolani, Mahesh, Davidson, Ben, Nesland, Jahn M, Wang, Ling-Zhi, Matsumura, Noriomi, Mandai, Masaki, Konishi, Ikuo, Goh, Boon-Cher, Chang, Jeffrey T, Thiery, Jean Paul, Mori, Seiichi
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2013
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721473/
https://ncbi.nlm.nih.gov/pubmed/23666744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201823
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