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MicroRNA-146 represses endothelial activation by inhibiting pro-inflammatory pathways

Activation of inflammatory pathways in the endothelium contributes to vascular diseases, including sepsis and atherosclerosis. We demonstrate that miR-146a and miR-146b are induced in endothelial cells upon exposure to pro-inflammatory cytokines. Despite the rapid transcriptional induction of the mi...

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Detalhes bibliográficos
Main Authors: Cheng, Henry S, Sivachandran, Nirojini, Lau, Andrew, Boudreau, Emilie, Zhao, Jimmy L, Baltimore, David, Delgado-Olguin, Paul, Cybulsky, Myron I, Fish, Jason E
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721471/
https://ncbi.nlm.nih.gov/pubmed/23733368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201202318
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