MEMBRANE POTENTIAL AND pH-DEPENDENT ACCUMULATION OF DECYNIUM-22 (1,1′-DIETHYL-2,2′-CYANINE IODIDE) FLUORESCENCE THROUGH OCT TRANSPORTERS IN ASTROCYTES

1,1′-Diethyl-2,2′-cyanine iodide (decynium22; D22) is a potent blocker of the organic cation family of transporters (EMT/OCT) known to move endogenous monoamines like dopamine and norepinephrine across cell membranes. Decynium22 is a cation with a relatively high affinity for all members of the OCT...

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Main Authors: Inyushin, Mikhail, Kucheryavykh, Yuri, Kucheryavykh, Lilia, Sanabria, Priscilla, Jiménez-Rivera, Carlos, Struganova, Irina, Eaton, Misty, Skatchkov, Serguei
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721433/
https://ncbi.nlm.nih.gov/pubmed/23875515
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