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Structural and Functional Properties of Platelet-Derived Growth Factor and Stem Cell Factor Receptors

The receptors for platelet-derived growth factor (PDGF) and stem cell factor (SCF) are members of the type III class of PTK receptors, which are characterized by five Ig-like domains extracellularly and a split kinase domain intracellularly. The receptors are activated by ligand-induced dimerization...

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Détails bibliographiques
Auteurs principaux: Heldin, Carl-Henrik, Lennartsson, Johan
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721287/
https://ncbi.nlm.nih.gov/pubmed/23906712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a009100
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