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Complexity of Receptor Tyrosine Kinase Signal Processing

Our knowledge of molecular mechanisms of receptor tyrosine kinase (RTK) signaling advances with ever-increasing pace. Yet our understanding of how the spatiotemporal dynamics of RTK signaling control specific cellular outcomes has lagged behind. Systems-centered experimental and computational approa...

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Detalhes bibliográficos
Main Authors: Volinsky, Natalia, Kholodenko, Boris N.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721286/
https://ncbi.nlm.nih.gov/pubmed/23906711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a009043
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