Transgenic pigs designed to express human α-galactosidase to avoid humoral xenograft rejection

The use of animals as a source of organs and tissues for xenotransplantation can overcome the growing shortage of human organ donors. However, the presence of xenoreactive antibodies in humans directed against swine Gal antigen present on the surface of xenograft donor cells leads to the complement...

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Main Authors: Zeyland, J., Gawrońska, B., Juzwa, W., Jura, J., Nowak, A., Słomski, R., Smorąg, Z., Szalata, M., Woźniak, A., Lipiński, D.
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2013
Teme:
Animal Genetics • Original Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720986/
https://ncbi.nlm.nih.gov/pubmed/23780397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13353-013-0156-y
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