Allogeneic transplants, Fas-signaling, and dysregulation of hepcidin

Hepatic iron overload is common in patients undergoing hematopoietic cell transplantation. We showed previously in a murine model that transplantation of allogeneic T cells induced iron deposition and down-regulation of hepcidin (Hamp) in hepatocytes. We hypothesized that hepatic injury was related...

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Hauptverfasser: Li, Xiang, Xu, Feng, Karoopongse, Ekapun, Marcondes, A. Mario, Lee, Kayoung, Kowdley, Kris V., Miao, Carol H., Trobridge, Grant D., Campbell, Jean S., Deeg, H. Joachim
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720784/
https://ncbi.nlm.nih.gov/pubmed/23707854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2013.05.012
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