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Nuclear mechanics: Lamin webs and pathological blebs

Anomalies in the three-dimensional shape of the nucleus are associated with a number of genetic diseases. These shape distortions include lobulated structures, with localized bulges referred to as nuclear blebs. Blebbing can result from mutations in genes encoding lamin intermediate filaments that f...

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Detalhes bibliográficos
Main Authors: Broedersz, Chase P., Brangwynne, Clifford P.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720744/
https://ncbi.nlm.nih.gov/pubmed/23697996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.25019
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