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A Novel Approach to Detect Cumulative Genetic Effects and Genetic Interactions in Crohn's Disease
BACKGROUND: Genome-wide association studies (GWAS) have identified at least 71 Crohn's disease (CD) genetic risk loci but the role of gene-gene interactions is unclear. The value of genetic variants in clinical practice is not defined due to limited explained heritability. MATERIALS AND METHODS...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3720692/ https://ncbi.nlm.nih.gov/pubmed/23598818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0b013e31828706a0 |
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