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A Novel Approach to Detect Cumulative Genetic Effects and Genetic Interactions in Crohn's Disease

BACKGROUND: Genome-wide association studies (GWAS) have identified at least 71 Crohn's disease (CD) genetic risk loci but the role of gene-gene interactions is unclear. The value of genetic variants in clinical practice is not defined due to limited explained heritability. MATERIALS AND METHODS...

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Detalhes bibliográficos
Main Authors: Wang, Ming-Hsi, Fiocchi, Claudio, Duerr, Richard H., Zhu, Xiaofeng, Ripke, Stephan, Achkar, Jean-Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720692/
https://ncbi.nlm.nih.gov/pubmed/23598818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0b013e31828706a0
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