Foot-and-mouth disease virus-like particles produced by a SUMO fusion protein system in Escherichia coli induce potent protective immune responses in guinea pigs, swine and cattle

Foot-and-mouth disease virus (FMDV) causes a highly contagious infection in cloven-hoofed animals. The format of FMD virus-like particles (VLP) as a non-replicating particulate vaccine candidate is a promising alternative to conventional inactivated FMDV vaccines. In this study, we explored a prokar...

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Detalhes bibliográficos
Main Authors: Guo, Hui-Chen, Sun, Shi-Qi, Jin, Ye, Yang, Shun-Li, Wei, Yan-Quan, Sun, De-Hui, Yin, Shuang-Hui, Ma, Jun-Wu, Liu, Zai-Xin, Guo, Jian-Hong, Luo, Jian-Xun, Yin, Hong, Liu, Xiang-Tao, Liu, Ding Xiang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720265/
https://ncbi.nlm.nih.gov/pubmed/23826638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1297-9716-44-48
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