Attenuated Salmonella choleraesuis-mediated RNAi targeted to conserved regions against foot-and-mouth disease virus in guinea pigs and swine

In this study, specific sequences within three genes (3D, VP4 and 2B) of the foot-and-mouth disease virus (FMDV) genome were determined to be effective RNAi targets. These sequences are highly conserved among different serotype viruses based on sequence analysis. Small interfering RNA (siRNA)-expres...

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Detalhes bibliográficos
Main Authors: Cong, Wei, Jin, Hong, Jiang, Chengda, Yan, Weiyao, Liu, Mingqiu, Chen, Jiulian, Zuo, Xiaoping, Zheng, Zhaoxin
Formato: Artigo
Idioma:Inglês
Publicado em: EDP Sciences 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826090/
https://ncbi.nlm.nih.gov/pubmed/20167192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1051/vetres/2010002
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