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Immunoglobulin G independent activation of the classical complement pathway by monosodium urate crystals.

10 mg of monosodium urate crystals reduced the CH50 of 1 ml of human serum by 57% after 30 min at 37 degrees C. C1, C4, and C3 depletion of 52, 68, and 46% were typical of classical pathway activation. C1 binding and activation occurred when urate crystals were incubated with isolated precursor C1,...

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Bibliografski detalji
Glavni autori: Giclas, P C, Ginsberg, M H, Cooper, N R
Format: Artigo
Jezik:Inglês
Izdano: 1979
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC372012/
https://ncbi.nlm.nih.gov/pubmed/438335
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