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Single-nucleotide polymorphisms in HORMAD1 may be a risk factor for azoospermia caused by meiotic arrest in Japanese patients

Genetic mechanisms are implicated as a cause of some male infertility, yet are poorly understood. Meiosis is unique to germ cells and essential for reproduction. The synaptonemal complex is a critical component for chromosome pairing, segregation and recombination. Hormad1 is essential for mammalian...

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Bibliografiske detaljer
Main Authors: Miyamoto, Toshinobu, Tsujimura, Akira, Miyagawa, Yasushi, Koh, Eitetsu, Namiki, Mikio, Horikawa, Michiharu, Saijo, Yasuaki, Sengoku, Kazuo
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720071/
https://ncbi.nlm.nih.gov/pubmed/22407170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aja.2011.180
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