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The tumor microenvironment modulates tamoxifen resistance in breast cancer: a role for soluble stromal factors and fibronectin through β1 integrin
Tamoxifen resistance has been largely attributed to genetic alterations in the epithelial tumor cells themselves, such as overexpression of HER-2/Neu. However, in the clinic, only about 15–20% of cases of HER-2/ Neu amplification has actually been correlated to the acquisition of endocrine resistanc...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3719875/ https://ncbi.nlm.nih.gov/pubmed/21935603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-011-1766-x |
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