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Affinity modulation of integrin alpha 5 beta 1: regulation of the functional response by soluble fibronectin
We report that a beta 1 integrin (alpha 5 beta 1) can exist in different affinity states for its soluble ligand, fibronectin. The alpha 5 beta 1 expressed by the erythroleukemic cell line K562 binds soluble fibronectin with low affinity (Kd > 1 microM), but is induced to bind it with 20-fold high...
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| Format: | Artigo |
|---|---|
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
1993
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2119780/ https://ncbi.nlm.nih.gov/pubmed/8458867 |
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