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Arginine-Rich Motifs Are Not Required for Hepatitis Delta Virus RNA Binding Activity of the Hepatitis Delta Antigen

Hepatitis delta virus (HDV) replication and packaging require interactions between the unbranched rodlike structure of HDV RNA and hepatitis delta antigen (HDAg), a basic, disordered, oligomeric protein. The tendency of the protein to bind nonspecifically to nucleic acids has impeded analysis of HDV...

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Autores principales: Daigh, Leighton H., Griffin, Brittany L., Soroush, Ali, Mamedov, Murad R., Casey, John L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719807/
https://ncbi.nlm.nih.gov/pubmed/23740973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00929-13
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