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Arginine-Rich Motifs Are Not Required for Hepatitis Delta Virus RNA Binding Activity of the Hepatitis Delta Antigen

Hepatitis delta virus (HDV) replication and packaging require interactions between the unbranched rodlike structure of HDV RNA and hepatitis delta antigen (HDAg), a basic, disordered, oligomeric protein. The tendency of the protein to bind nonspecifically to nucleic acids has impeded analysis of HDV...

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Detalhes bibliográficos
Main Authors: Daigh, Leighton H., Griffin, Brittany L., Soroush, Ali, Mamedov, Murad R., Casey, John L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719807/
https://ncbi.nlm.nih.gov/pubmed/23740973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00929-13
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