Coadministration of Atazanavir-Ritonavir and Zinc Sulfate: Impact on Hyperbilirubinemia and Pharmacokinetics

Atazanavir (ATV) causes an elevation of unconjugated hyperbilirubinemia (HBR) as a result of UDP glucuronyltransferase (UGT) 1A1 inhibition. Zinc sulfate (ZnSO(4)) reduces unconjugated hyperbilirubinemia in individuals with Gilbert's syndrome. We assessed the changes in total, conjugated, and u...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Moyle, Graeme, Else, Laura, Jackson, Akil, Back, David, Yapa, Manisha H., Seymour, Natalia, Ringner-Nackter, Lisa, Karolia, Zeenat, Gazzard, Brian, Boffito, Marta
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2013
Onderwerpen:
Pharmacology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719779/
https://ncbi.nlm.nih.gov/pubmed/23689708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00357-13
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items