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ARF6-Regulated Endocytosis of Growth Factor Receptors Links Cadherin-Based Adhesion to Canonical Wnt Signaling in Epithelia

Wnt signaling has an essential role in embryonic development as well as stem/progenitor cell renewal, and its aberrant activation is implicated in many diseases, including several cancers. β-Catenin is a critical component of Wnt-mediated transcriptional activation. Here we show that ARF6 activation...

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Bibliografiske detaljer
Main Authors: Pellon-Cardenas, Oscar, Clancy, James, Uwimpuhwe, Henriette, D'Souza-Schorey, Crislyn
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719676/
https://ncbi.nlm.nih.gov/pubmed/23716594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01698-12
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