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Lack of tRNA Modification Isopentenyl-A37 Alters mRNA Decoding and Causes Metabolic Deficiencies in Fission Yeast

tRNA isopentenyltransferases (Tit1) modify tRNA position 37, adjacent to the anticodon, to N(6)-isopentenyladenosine (i6A37) in all cells, yet the tRNA subsets selected for modification vary among species, and their relevance to phenotypes is unknown. We examined the function of i6A37 in Schizosacch...

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Detalhes bibliográficos
Main Authors: Lamichhane, Tek N., Blewett, Nathan H., Crawford, Amanda K., Cherkasova, Vera A., Iben, James R., Begley, Thomas J., Farabaugh, Philip J., Maraia, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719670/
https://ncbi.nlm.nih.gov/pubmed/23716598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00278-13
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