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Development of a Chimeric Plasmodium berghei Strain Expressing the Repeat Region of the P. vivax Circumsporozoite Protein for In Vivo Evaluation of Vaccine Efficacy

The development of vaccine candidates against Plasmodium vivax—the most geographically widespread human malaria species—is challenged by technical difficulties, such as the lack of in vitro culture systems and availability of animal models. Chimeric rodent Plasmodium parasites are safe and useful to...

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Autors principals: Espinosa, Diego A., Yadava, Anjali, Angov, Evelina, Maurizio, Paul L., Ockenhouse, Christian F., Zavala, Fidel
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719583/
https://ncbi.nlm.nih.gov/pubmed/23716612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00461-13
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