Protective Efficacy of a Plasmodium vivax Circumsporozoite Protein-Based Vaccine in Aotus nancymaae Is Associated with Antibodies to the Repeat Region

We have previously reported that Vivax Malaria Protein 001 (VMP001), a vaccine candidate based on the circumsporozoite protein of Plasmodium vivax, is immunogenic in mice and rhesus monkeys in the presence of various adjuvants. In the present study, we evaluated the immunogenicity and efficacy of VM...

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Detalhes bibliográficos
Main Authors: Yadava, Anjali, Hall, Cysha E., Sullivan, JoAnn S., Nace, Douglas, Williams, Tyrone, Collins, William E., Ockenhouse, Christian F., Barnwell, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199514/
https://ncbi.nlm.nih.gov/pubmed/25329054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003268
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