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Assessment of alpha-1-antitrypsin deficiency heterozygosity as a risk factor in the etiology of emphysema. Physiological comparison of adult normal and heterozygous protease inhibitor phenotype subjects from a random population.

For plethysmographic studies of lung mechanics and measurement of pulmonary diffusing capacity, 62 subjects were drawn from a randomly selected population sample. Data obtained from the 24 subjects of heterozygous phenotype for alpha-1-antitrypsin deficiency (PiMZ) were compared by age group with da...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Principais autores: McDonagh, D J, Nathan, S P, Knudson, R J, Lebowitz, M D
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1979
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371953/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/311786/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109303
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