Development of Biotin-Prototrophic and -Hyperauxotrophic Corynebacterium glutamicum Strains

To develop the infrastructure for biotin production through naturally biotin-auxotrophic Corynebacterium glutamicum, we attempted to engineer the organism into a biotin prototroph and a biotin hyperauxotroph. To confer biotin prototrophy on the organism, the cotranscribed bioBF genes of Escherichia...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ikeda, Masato, Miyamoto, Aya, Mutoh, Sumire, Kitano, Yuko, Tajima, Mei, Shirakura, Daisuke, Takasaki, Manami, Mitsuhashi, Satoshi, Takeno, Seiki
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Biotechnology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719520/
https://ncbi.nlm.nih.gov/pubmed/23709504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00828-13
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