Engineering of Corynebacterium glutamicum with an NADPH-Generating Glycolytic Pathway for l-Lysine Production

A sufficient supply of NADPH is a critical factor in l-lysine production by Corynebacterium glutamicum. Endogenous NAD-dependent glyceraldehyde 3-phosphate dehydrogenase (GAPDH) of C. glutamicum was replaced with nonphosphorylating NADP-dependent glyceraldehyde 3-phosphate dehydrogenase (GapN) of St...

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Hlavní autoři: Takeno, Seiki, Murata, Ryosuke, Kobayashi, Ryosuke, Mitsuhashi, Satoshi, Ikeda, Masato
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
Physiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976228/
https://ncbi.nlm.nih.gov/pubmed/20851994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01464-10
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