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Targeting HER2/neu with a fully human IgE to harness the allergic reaction against cancer cells

Breast and ovarian cancer are two of the leading causes of cancer deaths among women in the United States. Overexpression of the HER2/neu oncoprotein has been reported in patients affected with breast and ovarian cancers, and is associated with poor prognosis. To develop a novel targeted therapy for...

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Detalhes bibliográficos
Main Authors: Daniels, Tracy R., Leuchter, Richard K., Quintero, Rafaela, Helguera, Gustavo, Rodríguez, José A., Martínez-Maza, Otoniel, Schultes, Birgit C., Nicodemus, Christopher F., Penichet, Manuel L.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719406/
https://ncbi.nlm.nih.gov/pubmed/22127364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-011-1150-z
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