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Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

Microglia are the resident macrophages of the central nervous system and are associated with the pathogenesis of many neurodegenerative and brain inflammatory diseases; however, the origin of adult microglia remains controversial. We show that postnatal hematopoietic progenitors do not significantly...

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Main Authors: Ginhoux, Florent, Greter, Melanie, Leboeuf, Marylene, Nandi, Sayan, See, Peter, Gokhan, Solen, Mehler, Mark F., Conway, Simon J., Ng, Lai Guan, Stanley, E. Richard, Samokhvalov, Igor M., Merad, Miriam
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719181/
https://ncbi.nlm.nih.gov/pubmed/20966214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1194637
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