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Listerin-Dependent Nascent Protein Ubiquitination Relies on Ribosome Subunit Dissociation

Quality control of defective mRNAs relies on their translation to detect the lesion. Aberrant proteins are therefore an obligate byproduct of mRNA surveillance and must be degraded to avoid disrupting protein homeostasis. These defective translation products are thought to be ubiquitinated at the ri...

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Detalhes bibliográficos
Main Authors: Shao, Sichen, von der Malsburg, Karina, Hegde, Ramanujan S.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719020/
https://ncbi.nlm.nih.gov/pubmed/23685075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.04.015
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