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miR-19a: An Effective Regulator of SOCS3 and Enhancer of JAK-STAT Signalling

Suppressors of cytokine signalling (SOCS) proteins are classic inhibitors of the Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway. Many cytokines and pathogenic mediators induce expression of SOCS, which act in a negative feedback loop to inhibit further signal transd...

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Main Authors: Collins, Aideen S., McCoy, Claire E., Lloyd, Andrew T., O’Farrelly, Cliona, Stevenson, Nigel J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718810/
https://ncbi.nlm.nih.gov/pubmed/23894411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069090
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