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Mitochondrial Autophagy Involving Renal Injury and Aging Is Modulated by Caloric Intake in Aged Rat Kidneys

BACKGROUND: A high-calorie (HC) diet induces renal injury and promotes aging, and calorie restriction (CR) may ameliorate these responses. However, the effects of long-term HC and CR on renal damage and aging have been not fully determined. Autophagy plays a crucial role in removing protein aggregat...

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Autors principals: Cui, Jing, Shi, Suozhu, Sun, Xuefeng, Cai, Guangyan, Cui, Shaoyuan, Hong, Quan, Chen, Xiangmei, Bai, Xue-Yuan
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718786/
https://ncbi.nlm.nih.gov/pubmed/23894530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069720
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