Rescue of Amyloid-Beta-Induced Inhibition of Nicotinic Acetylcholine Receptors by a Peptide Homologous to the Nicotine Binding Domain of the Alpha 7 Subtype

Alzheimer's disease (AD) is characterized by brain accumulation of the neurotoxic amyloid-β peptide (Aβ) and by loss of cholinergic neurons and nicotinic acetylcholine receptors (nAChRs). Recent evidence indicates that memory loss and cognitive decline in AD correlate better with the amount of...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Nery, Arthur A., Magdesian, Margaret H., Trujillo, Cleber A., Sathler, Luciana B., Juliano, Maria A., Juliano, Luiz, Ulrich, Henning, Ferreira, Sergio T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718777/
https://ncbi.nlm.nih.gov/pubmed/23894286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067194
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