Sitagliptin Reduces Hyperglycemia and Increases Satiety Hormone Secretion More Effectively When Used with a Novel Polysaccharide in Obese Zucker Rats()

The novel polysaccharide (NPS) PolyGlycopleX (PGX) has been shown to reduce glycemia. Pharmacological treatment with sitagliptin, a dipeptidyl peptidase 4 (DPP4) inhibitor, also reduces glycemia by increasing glucagon-like peptide-1 (GLP-1). Our objective was to determine if using NPS in combination...

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Autori principali: Reimer, Raylene A., Grover, Gary J., Koetzner, Lee, Gahler, Roland J., Juneja, Prateek, Lyon, Michael R., Wood, Simon
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718709/
https://ncbi.nlm.nih.gov/pubmed/22915295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/jn.112.163204
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