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Interaction of Platelet Membrane Receptors with von Willebrand Factor, Ristocetin, and the Fc Region of Immunoglobulin G

The agglutination of human platelets by ristocetin and von Willebrand factor was inhibited by aggregated immunoglobulin (Ig)G and by Fc fragments of IgG, but not by Fab, F(ab′)(2) or pFc fragments of IgG. Because this inhibition occurred with formalin-fixed platelets as well as with normal platelets...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Moore, Anne, Ross, Gordon D., Nachman, Ralph L.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1978
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371865/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/309473/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109210
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