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Interaction of Platelet Membrane Receptors with von Willebrand Factor, Ristocetin, and the Fc Region of Immunoglobulin G

The agglutination of human platelets by ristocetin and von Willebrand factor was inhibited by aggregated immunoglobulin (Ig)G and by Fc fragments of IgG, but not by Fab, F(ab′)(2) or pFc fragments of IgG. Because this inhibition occurred with formalin-fixed platelets as well as with normal platelets...

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Pubblicato in:J Clin Invest
Autori principali: Moore, Anne, Ross, Gordon D., Nachman, Ralph L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1978
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371865/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/309473/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109210
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