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Evidence of complete cellular repair of 1,N(6)-ethenoadenine, a mutagenic and potential damage for human cancer, revealed by a novel method
1,N(6)-Ethenoadenine (εA) is generated endogenously by lipid peroxidation and exogenously by tumorigenic industrial agents, vinyl chloride, and vinyl carbamate. εA detected in human tissues causes mutation and is implicated in liver, colon and lung cancers. N-methyl purine DNA-glycosylase (MPG) is t...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3718636/ https://ncbi.nlm.nih.gov/pubmed/18373235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-008-9737-1 |
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