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Modulation of allostery by protein intrinsic disorder

Allostery is an intrinsic property of many globular proteins and enzymes that is indispensable for cellular regulatory and feedback mechanisms. Recent theoretical(1) and empirical(2) observations indicate that allostery is also manifest in intrinsically disordered proteins (IDPs), which account for...

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Main Authors: Ferreon, Allan Chris M., Ferreon, Josephine C., Wright, Peter E., Deniz, Ashok A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718496/
https://ncbi.nlm.nih.gov/pubmed/23783631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12294
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