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Modulation of allostery by protein intrinsic disorder
Allostery is an intrinsic property of many globular proteins and enzymes that is indispensable for cellular regulatory and feedback mechanisms. Recent theoretical(1) and empirical(2) observations indicate that allostery is also manifest in intrinsically disordered proteins (IDPs), which account for...
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Hauptverfasser: | , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2013
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3718496/ https://ncbi.nlm.nih.gov/pubmed/23783631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12294 |
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