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Gadolinium and 5-Aminolevulinic Acid-induced Protoporphyrin IX Levels in Human Gliomas: An Ex Vivo Quantitative Study to Correlate Protoporphyrin IX Levels and Blood-Brain Barrier Breakdown

In recent years, 5-aminolevulinic acid (ALA)-induced protoporphyrin IX (PpIX) fluorescence guidance has been used as a surgical adjunct to improve the extent of resection of gliomas. Exogenous administration of ALA prior to surgery leads to the accumulation of red fluorescent PpIX in tumor tissue th...

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Bibliografiske detaljer
Main Authors: Valdés, Pablo A., Moses, Ziev B., Kim, Anthony, Belden, Clifford J., Wilson, Brian C., Paulsen, Keith D., Roberts, David W., Harris, Brent T.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718468/
https://ncbi.nlm.nih.gov/pubmed/22878664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e31826775a1
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