δ-aminolevulinic acid–induced protoporphyrin IX concentration correlates with histopathologic markers of malignancy in human gliomas: the need for quantitative fluorescence-guided resection to identify regions of increasing malignancy

Extent of resection is a major goal and prognostic factor in the treatment of gliomas. In this study we evaluate whether quantitative ex vivo tissue measurements of δ-aminolevulinic acid–induced protoporphyrin IX (PpIX) identify regions of increasing malignancy in low- and high-grade gliomas beyond...

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Detalhes bibliográficos
Main Authors: Valdés, Pablo A., Kim, Anthony, Brantsch, Marco, Niu, Carolyn, Moses, Ziev B., Tosteson, Tor D., Wilson, Brian C., Paulsen, Keith D., Roberts, David W., Harris, Brent T.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145475/
https://ncbi.nlm.nih.gov/pubmed/21798847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor086
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