The stimulus-secretion coupling of glucose-induced insulin release. Metabolic and functional effects of NH4+ in rat islets.

NH4+ caused a dose-related, rapid, and reversible inhibition of glucose-stimulated insulin release by isolated rat islets. It also inhibited glyceraldehyde-, Ba2+-, and sulfonylurea-stimulated insulun secretion. NH4+ failed to affect glucose utilization and oxidation, glucose-stimulated proinsulin b...

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Autores principales: Sener, A, Hutton, J C, Kawazu, S, Boschero, A C, Somers, G, Devis, G, Herchuelz, A, Malaisse, W J
Formato: Artigo
Lenguaje:Inglês
Publicado: 1978
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC371839/
https://ncbi.nlm.nih.gov/pubmed/29912
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