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Synthesis of mixed-chain phosphatidylcholines including coumarin fluorophores for FRET-based kinetic studies of phospholipase A(2) enzymes

Phospholipase A(2) (PLA(2)) enzymes catalyze the hydrolysis of the sn-2 ester linkage of glycerophospholipids to produce fatty acids and lysophospholipids. A significant number of mammalian phospholipases comprise a family of secreted PLA(2) enzymes, found in specific tissues and cellular locations,...

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Hlavní autoři: Wang, Manlin, Pinnamaraju, Susmitha, Ranganathan, Radha, Hajdu, Joseph
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718315/
https://ncbi.nlm.nih.gov/pubmed/23727005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chemphyslip.2013.05.003
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