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LIM kinase 1 promotes endothelial barrier disruption and neutrophil infiltration in mouse lungs

RATIONALE: Disruption of endothelial barrier function and neutrophil-mediated injury are two major mechanisms underlying the pathophysiology of sepsis-induced acute lung injury (ALI). Recently we reported that endotoxin induced activation of RhoA in mice lungs that led to the disruption of endotheli...

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Detalhes bibliográficos
Main Authors: Gorovoy, Matvey, Han, Jingyan, Pan, Haiyun, Welch, Emily, Neamu, Radu, Jia, Zhengping, Predescu, Dan, Vogel, Stephen, Minshall, Richard, Ye, Richard D., Malik, Asrar B., Voyno-Yasenetskaya, Tatyana
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718297/
https://ncbi.nlm.nih.gov/pubmed/19679840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.195883
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