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Molecular logistics using cytocleavable polyrotaxanes for the reactivation of enzymes delivered in living cells

The intracellular delivery of enzymes is an essential methodology to extend their therapeutic application. Herein, we have developed dissociable supermolecule-enzyme polyelectrolyte complexes based on reduction-cleavable cationic polyrotaxanes (PRXs) for the reactivation of delivered enzymes. These...

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מידע ביבליוגרפי
Main Authors: Tamura, Atsushi, Ikeda, Go, Seo, Ji-Hun, Tsuchiya, Koji, Yajima, Hirofumi, Sasaki, Yoshihiro, Akiyoshi, Kazunari, Yui, Nobuhiko
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718191/
https://ncbi.nlm.nih.gov/pubmed/23872688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02252
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