Highly multiplexed single-cell analysis of formalin-fixed, paraffin-embedded cancer tissue

Limitations on the number of unique protein and DNA molecules that can be characterized microscopically in a single tissue specimen impede advances in understanding the biological basis of health and disease. Here we present a multiplexed fluorescence microscopy method (MxIF) for quantitative, singl...

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Hlavní autoři: Gerdes, Michael J., Sevinsky, Christopher J., Sood, Anup, Adak, Sudeshna, Bello, Musodiq O., Bordwell, Alexander, Can, Ali, Corwin, Alex, Dinn, Sean, Filkins, Robert J., Hollman, Denise, Kamath, Vidya, Kaanumalle, Sireesha, Kenny, Kevin, Larsen, Melinda, Lazare, Michael, Li, Qing, Lowes, Christina, McCulloch, Colin C., McDonough, Elizabeth, Montalto, Michael C., Pang, Zhengyu, Rittscher, Jens, Santamaria-Pang, Alberto, Sarachan, Brion D., Seel, Maximilian L., Seppo, Antti, Shaikh, Kashan, Sui, Yunxia, Zhang, Jingyu, Ginty, Fiona
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718135/
https://ncbi.nlm.nih.gov/pubmed/23818604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1300136110
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