Highly multiplexed single-cell analysis of formalin-fixed, paraffin-embedded cancer tissue

Limitations on the number of unique protein and DNA molecules that can be characterized microscopically in a single tissue specimen impede advances in understanding the biological basis of health and disease. Here we present a multiplexed fluorescence microscopy method (MxIF) for quantitative, singl...

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Detalhes bibliográficos
Main Authors: Gerdes, Michael J., Sevinsky, Christopher J., Sood, Anup, Adak, Sudeshna, Bello, Musodiq O., Bordwell, Alexander, Can, Ali, Corwin, Alex, Dinn, Sean, Filkins, Robert J., Hollman, Denise, Kamath, Vidya, Kaanumalle, Sireesha, Kenny, Kevin, Larsen, Melinda, Lazare, Michael, Li, Qing, Lowes, Christina, McCulloch, Colin C., McDonough, Elizabeth, Montalto, Michael C., Pang, Zhengyu, Rittscher, Jens, Santamaria-Pang, Alberto, Sarachan, Brion D., Seel, Maximilian L., Seppo, Antti, Shaikh, Kashan, Sui, Yunxia, Zhang, Jingyu, Ginty, Fiona
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718135/
https://ncbi.nlm.nih.gov/pubmed/23818604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1300136110
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